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Lars Björndahl (cv)
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Lars Björndahl established LB Andrologikonsult in 1995 primarily to support the Andrology Laboratory at the Karolinska University Hospital, Solna, Sweden. I have been part of the development of this unit from the early beginning in the late 1980:ies including the process of accreditation by the Swedish accreditation authority, Swedac, in 2007.
Recent Work
Project leader for national investigations concerning postmortal viral testing as a part of tne National Tissue Project,
Development of quality manuals, checklists and other materials for the Swedish National Tissueproject (implementation of EG directives on Cells and Tissues).
Consultancy for the establishment of an andrology laboratory, University of Dundee, Scotland.
Quality Control and Assessment, teaching and training, Andrology Laboratory, Karolinska University Hospital, Stockholm, Sweden.
Curriculum vitae
Education
- Specialist in clinical chemistry 1992
- Licensed physician in 1990
- Ph D, Department of Physiology, Karolinska Institutet, 1982-1986
- MD, Karolinska Institutet 1976-1982
Work as scientist/physician
- Consultant in laboratory andrology, part time 1995-2007, full time since 2007
- Director of Andrology, Assisted Conception Unit, Birmingham Women's Hospital, Birmingham, UK; 2004-2005.
- Scientist in Reproductive Biology (Assisted Conception Unit, Birmingham Women's Hospital, Birmingham, UK; 2002-2004)
- Research Fellow and Honorary Senior Lecturer in Reproductive Biology (University of Birmingham, UK, 2001-2005)
- Ward physician, Andrology Laboratory (Reproductive Medicine Centre, Karolinska University Hospital, Solna; 1993-1998)
- Clinical Chemistry: intern physician 1990-1993
- Intern physician (medicine, surgery, anaesthetics, ortopedics, psychiatry, district health service; Köpings Lasarett (1980), Sabbatsbergs hospital (1987-89), Beckomberga hospital (1989), Lidingö hospital (1981-84) and Bergshamra Vårdcentral, Solna (1990)
- Assistant teacher, junior research fellow and substituting senior university lecturer (Dept of Physiology, Karolinska Institutet, 1979-1990)
Among scientific commissions
- Associate Editor, Human Reproduction (2010-)
- Member of Steering Group for the Karolinska Network for Reproduction, Growth and Development (2009-)
- Science Secretary of the Swedish Society of Andrology (2009-)
- President in NAFA (2007-)
- Co-ordinator of the ESHRE Special Interest Group in Andrology (2004-2008)
- Member of the editorial committee for the fifth edition of the WHO manual on semen analysis (2005-2007)
- Sekretary in the NAFA Workgroup for semen analysis techniques (1995-2002)
Ph.D. students
- Emma Holmes
- Emelie Ekwurtzel
Scientific publications
A] Published original work
| 2008 |
Kirkman-Brown J and Björndahl L. Evaluation of a disposable plastic Neubauer counting chamber for semen analysis.
Fertil Steril, 91(2): 627-31. |
| 2006 |
Björndahl L., Kirkman-Brown J., Hart G., Rattle S. and Barratt C.L. Development of a novel home sperm test. Hum Reprod; 21(1): 145-9. |
| 2005 |
Bjorndahl L., Mohammadieh M., Pourian M., Söderlund I. and Kvist U. Contamination by seminal plasma factors during sperm selection. J Androl; 26(2): 170-3. |
| 2005 |
Moseley F.L., Jha K.N., Björndahl L., Brewis I.A., Publicover S.J., Barratt C.L. and Lefievre L. Protein tyrosine phosphorylation, hyperactivation and progesterone-induced acrosome reaction are enhanced in IVF media: an effect that is not associated with an increase in protein kinase A activation. Mol Hum Reprod; 11(7): 523-9 |
| 2004 |
Pixton, Deeks, Flesch, Moseley, Björndahl, Ashton, Barratt & Brewis. Sperm proteome mapping of a patient who experienced failed fertilization at IVF reveals altered expression of at least twenty proteins compared to fertile donors: case report. Hum Reprod. 19(6):1438-47. |
| 2004 |
Björndahl, Söderlund, Johansson, Mohammadieh, Pourian, Kvist U. Why the WHO recommendations for eosin-nigrosin staining techniques for human sperm vitality assessment must change. J Androl. 25(5):671-8. |
| 2003 |
Björndahl, Söderlund & Kvist. Evaluation of the one-step eosin-nigrosin staining technique for human sperm vitality assessment. Hum Reprod 18(4):813-816. |
| 2003 |
Ola, Afnan, Papaioannou, Sharif, Björndahl & Coomarasamy. Accuracy of sperm-cervical mucus penetration tests in evaluating sperm motility in semen: a systematic quantitative review. Human Reprod 18(5):1037-1046. |
| 2002 |
Björndahl, Barratt, Fraser, Kvist & Mortimer. ESHRE basic semen analysis courses 1995-1999: immediate beneficial effects of standardized training. Hum Reprod, 17: 1399-1405. |
| 2002 |
Kvist & Björndahl. Editorial for Manual on Basic Semen Analysis, ESHRE Monographs, Oxford University Press, Oxford |
| 2002 |
Cooper, Björndahl, Vreeburg & Nieschlag. Semen analysis and external quality control schemes for semen analysis need global standardisation. Int J Androl, 25(5):306-311 |
| 1995 |
Pourian, Kvist, Björndahl & Oliw. Rapid and Slow Hydroxylators of Seminal E Prostaglandins among Men in Barren Unions. Andrologia, 27: 71-79. |
| 1992 |
Kjellberg, Björndahl & Kvist. Sperm chromatin stability and zinc binding properties in semen from men in barren unions. Int J Androl, 15:103-113. |
| 1991 |
Björndahl, Kjellberg & Kvist, Ejaculatory sequence in men with low sperm chromatin zinc, Int J Androl, 14: 174-178. |
| 1990 |
Björndahl & Kvist, Influence of seminal vesicular fluid on content of zinc in human sperm chromatin, Int J Androl, 13: 232-237. |
| 1990 |
Kvist, Kjellberg, Björndahl, Soufir & Arver, Seminal fluid from men with agenesis of the Wolffian ducts: zinc binding properties and effects on sperm chromatin stability, Int J Androl, 13: 245-252 |
| 1990 |
Rosenborg, Rao, Björndahl, Kvist, Pousette, Åkerlöf & Fredricsson, Changes in human sperm chromatin stability during preparation for in vitro fertilization, Int J Androl, 13: 287-296. |
| 1988 |
Kvist, Kjellberg, Björndahl, Hammar & Roomans, Zinc in sperm chromatin and chromatin stability in fertile men and men in barren unions, Scand J Urol Nephrol 22: 1-6. |
| 1987 |
Casswall, Björndahl & Kvist, Cadmium interacts with a zinc-dependent stability of the human sperm chromatin, Trace Elem Electrol Health Disease 1: 85-87. |
| 1987 |
Kvist, Björndahl & Kjellberg, Sperm nuclear zinc, chromatin stability and male fertility, Scanning Microscopy 1: 1241-1247. |
| 1986 |
Björndahl, Kjellberg, Roomans & Kvist, The human sperm nucleus takes up zinc at ejaculation, Int J Androl 9: 77-80. |
| 1985 |
Björndahl & Kvist, Loss of an intrinsic capacity for human sperm chromatin decondensation, Acta Physiol Scand 124: 189-194. |
| 1985 |
Kvist & Björndahl, Zinc preserves an inherent capacity for human sperm chromatin decondensation, Acta Physiol Scand 124: 195-200. |
| 1985 |
Kvist, Björndahl, Roomans & Lindholmer, Nuclear zinc in human epididymal and ejaculated spermatozoa, Acta Physiol Scand 125: 297-303. |
| 1982 |
Björndahl & Kvist, Importance of zinc for human sperm head-tail connection, Acta Physiol Scand 116: 51-55. |
| 1982 |
Roomans, Lundevall, Björndahl & Kvist, Removal of zinc from subcellular regions of ejaculated human spermatozoa by EDTA treatment studied by X-ray microanalysis, Int J Androl 5: 478-486. |
B] Reviews and commentaries
| 2010 |
Barratt CLR, Aitken RJ, Björndahl L, Carrell D, de Boer P, Kvist U, Lewis SEM, Perreault SD, Perry MJ, Ramos L, Robaire B, Ward S and Zini A. Sperm DNA: organization, protection and vulnerability: from basic science to clinical applications—a position report. Human Reproduction;
doi: 10.1093/humrep/dep465 |
2010 |
Björndahl L and Kvist U. Human sperm chromatin stabilization: a proposed model including zinc bridges,
Molecular Human Reproduction, Vol.16, 23–29. |
2010 |
Björndahl L. The usefulness and significance of assessing rapidly progressive spermatozoa.
Asian Journal of Andrology; 12: 33–35. |
2008 |
Björndahl L and Haugen TB. Hva forteller saedanalysen? Norsk Legetidskrift, 128(3):320-3. |
| 2006 |
Björndahl L, Connelly T, Kirkman-Brown J and Barratt CLR. 2006. Reply: Development of a novel home sperm test -temperature range. Human Reproduction, 3028-3029. |
| 2006 |
Björndahl L, Kirkman-Brown J and Barratt CLR. Reply: Development of a novel home sperm test – What are the limitations? Human Reproduction 3030-3031. |
| 2005 |
Björndahl L. and Barratt C.L. Semen analysis: setting standards for the measurement of sperm numbers. J Androl; 26(1): 11 |
| 2004 |
Bjorndahl L., Tomlinson M. and Barratt C.L. Raising standards in semen analysis: professional and personal responsibility. J Androl; 25(6): 862-3. |
| 2003 |
Björndahl & Kvist. Sequence of ejaculation affects the spermatozoon as a carrier and its message. Reprod Biomed Online: 7(4): 440-448. |
C] Books and book chapters
| 2010 |
Cooper et al (eds.) WHO laboratory manual for the examination and processing of human semen. World Health Organization, Department of Reproductive Health and
Research,
WHO Geneva, Switzerland, pp 1-287. |
| 2002 |
Kvist & Björndahl (eds.) Manual on Basic Semen Analysis (NAFA-ESHRE 2002), ESHRE Monograph, Oxford University Press, Oxford. |
| 1998 |
Björndahl & Kvist, Basic Semen Analysis Courses: experiences in Scandinavia, In Modern ART in the 2000s (eds Ombelet et al), Parthenon Publishing Broup, New York-London, pp 91-102. |
| 1991 |
Kvist, Björndahl, Kjellberg, Rodriguez-Martinez & Plöen. Importance of zinc for stabilization of sperm chromatin. In Comparative Spermatology 20 years after (ed Baccetti), Raven Press, New York, pp 49-53. |
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